José C. Principe is a Distinguished Professor of Electrical and Biomedical Engineering at the University of Florida, Gainesville, where he teaches advanced signal processing and artificial neural network modeling. He is a BellSouth Professor, and is the Founder and Director of the University of Florida Computational NeuroEngineering Laboratory. His research is in the areas of biomedical signal processing, brain machine interfaces, nonlinear dynamics, and adaptive systems theory (information theoretic learning).

Principe is Editor in Chief of IEEE Transactions on Biomedical Engineering, President of the International Neural Network Society, and formal Secretary of the Technical Committee on Neural Networks of the IEEE Signal Processing Society. He is also a member of the Scientific Board of the Food and Drug Administration, and a member of the Advisory Board of the University of Florida Brain Institute.